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However, as with any pharmaceutical product, there are substantial risks and uncertainties in the process of drug research, development, and commercialization. Sensitive CYP2C8, CYP2C19, CYP3A, P-gP, BCRP Substrates: Concomitant use with moderate CYP3A inducers. The primary endpoint for the Phase 3 MONARCH 2 study.

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